A Dose of Reality with Charles Spence

Von: Charles Spence
  • Inhaltsangabe

  • Welcome to “A Dose of Reality”, the podcast where we infuse insight, laughter, and practical wisdom into the world of clinical leadership and career development. Hosted by Charles Spence, each episode offers a deep dive into the challenges and triumphs of clinical leadership, providing listeners with meaningful conversations, career insights, and a dose of inspiration to navigate their professional journeys. Whether you're a director, a C-level executive, or a clinical researcher in oncology bio-techs, this podcast is designed to empower you with the knowledge and tools needed to excel in your field. So, visit our website at www.discera-search.com, and tune in to A Dose of Reality for your prescription of career wisdom, leadership insights, and a healthy dose of laughter. Subscribe now and join us on the journey to becoming global clinical leaders!
    Copyright 2025 Charles Spence
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  • Gertjan Bartlema, Co-founder Populus Bio and CEO of Immodulon Therapeutics. on Innovation in Biotechs
    Jan 8 2025

    In this episode, I spoke with Gertjan Bartlema, the co-founder Populus Bio and CEO of Immodulon Therapeutics. Over 20 years in big pharma at Celgene/Amgen and then moved into the fast pace world of biotech. From here, he has been challenging the status quo and asking the question “Is our current drug development approaches sustainable?”. Gertjan highlights the need for better clinical trial designs and the importance of making objective decisions based on data. He also offers valuable insights for aspiring executives on leadership and team dynamics.

    Here's what you're in:

    • How many drugs fail end-points due to Bad Leadership?
    • Why does Gertjan believe sequential and traditional drug Development can kill innovation within Drug Development?.
    • What advice does Gertjan give to those wanting to become a CEO?


    Timestamps:

    02:53 The Abraxane Course Correction

    06:03 Gertjan’s Journey into Life Sciences

    10:40 Leaving Celgene and New Ventures

    15:50 Bayesian Statistics in Clinical Studies

    19:27 Mistakes Companies Are Still Making Today

    25:38 The Ambitious People

    35:46 Advice for Aspiring Executives


    About Gertjan

    Gertjan Bartlemais co-founder of Populus Bio and current CEO of Immodulon Therapeutics which is running cancer trials focusing on a broad spectrum immunomodulator. He is a global biotech executive with extensive experience in EU and US operational roles and he is a member of founding Celgene EMEA management establishing EU footprint and launching Revlimid. Prior to joining Immodulon, he was the Chief Business Officer of Vico Therapeutics, and spent 12 years with Celgene, where he led the trial of Revlimid. Gertjan holds MSc in Economics from Maastricht University.


    Connect with Gertjan

    LinkedIn: https://www.linkedin.com/in/gertjan-bartlema/

    Populus Bio: https://populusbio.com/

    Immodulon Therapeutics: https://www.immodulon.com/


    About me

    My name is Charles Spence and I lead Discera. After many years working in the life-science recruitment world, I decided to work for myself. Before doing recruitment I graduated with a biomedical degree, have worked in hospitals (including translation work in Seoul, South Korea), and also spent a year working in diabetes research in Stockholm. After doing research and travel, a career in business and science felt the most appropriate.

    In 2023, I decided to launch his firm - Discera Search. A firm committed to solving the biggest talent needs of early clinical stage SME biotechs on the East Coast and DACH.


    Connect with me:

    LinkedIn:https://www.linkedin.com/in/charles-spence-clinical/

    Website: https://www.discera-search.com/



    Opinions and comments expressed by the guest do not represent the company and are fully their own.



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    38 Min.
  • The 3 Most Common Rejection Reasons During an Interview
    Dec 30 2024

    In this episode, I discuss the three most common reasons hiring managers reject candidates, focusing on aspects that are often within the candidate's control. I highlight the importance of cultural fit, alignment of interests, and clarity in communication during interviews. I give tips to improve your interview performance and avoid common pitfalls that lead to rejection.

    Here's what you're in:

    • How cultural fit can be influenced by candidate behavior?
    • How using vague terms like 'strategy' can lead to misunderstandings?
    • Why building rapport with interviewers is crucial for success?


    Timestamps:

    01:09 Background Story

    03:37 Not a Good Cultural Fit

    07:29 Candidates Going To Get Bored/ Not Hands-on Enough

    12:01 Not Giving Straight to the Point Answers

    16:52 Summary


    About Me

    My name is Charles Spence and I lead Discera. After many years working in the life-science recruitment world, I decided to work for myself. Before doing recruitment I graduated with a biomedical degree, have worked in hospitals (including translation work in Seoul, South Korea), and also spent a year working in diabetes research in Stockholm. After doing research and travel, a career in business and science felt the most appropriate.

    In 2023, I decided to launch his firm - Discera Search. A firm committed to solving the biggest talent needs of early clinical stage SME biotechs on the East Coast and DACH.


    Connect with me:

    LinkedIn: https://www.linkedin.com/in/charles-spence-clinical/

    Website: https://www.discera-search.com/


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    18 Min.
  • The Most Common Hiring Mistakes by Hiring Managers in 2024 ft. Caroline Vermeulen, Eminence
    Dec 16 2024

    In this episode, I talked with Caroline Vermeulen, Recruitment & HR at Eminence, as she discussed into the details of the hiring process, highlighting the value of putting candidates first. She gave insights on common mistakes in recruiting, the importance of authenticity in communication, and the relationship between hiring managers and recruiters.

    Caroline and I also shared stories of both our best and worst hiring experiences, emphasizing out the need for clear expectations and good communication. Our conversation wraps up with a round of quickfire questions, providing more tips on recruitment best practices.


    Here's what you're in:

    • What are the most common hiring mistakes and how does that affect things later on?
    • How long should a CV be? How long should an interview be?
    • To give or not to give controversial feedback to candidates?


    Timestamps:

    01:50 Introduction and Career Background

    03:16 Caroline's New Mission: candidate-first

    06:19 Common Mistakes in Recruitment Processes

    09:31 Importance of Authenticity in Communication

    11:11 Communication Strategies with Hiring Managers

    16:35 Building a Smooth and Clean Recruitment Process

    22:43 Best and Worst Experience in Recruitment

    34:00 Quickfire Questions and Insights


    About Caroline

    Caroline Vermeulen is a Recruitment & HR at Eminence. She has an educational background of Bsc in Life sciences/Biotechnology, has over a decade of experience in the industry, including early-phase trials for generics, cell and gene therapies, immunotherapies, and pain medications, and has helped over a thousand candidates find jobs as a recruiter. Transitioning from agency to corporate recruitment, she faced challenges due to the complexities of corporate structures and the challenges in communication. Now, she is excited to launch her new business, candidate-first.com, focused on delivering quality candidate responses.


    Connect with Caroline

    LinkedIn: https://www.linkedin.com/in/carolinevermeulen1/

    Website: www.candidate-first.com


    About Me

    My name is Charles Spence and I lead Discera. After many years working in the life-science recruitment world, I decided to work for myself. Before doing recruitment I graduated with a biomedical degree, have worked in hospitals (including translation work in Seoul, South Korea), and also spent a year working in diabetes research in Stockholm. After doing research and travel, a career in business and science felt the most appropriate.

    In 2023, I decided to launch his firm - Discera Search. A firm committed to solving the biggest talent needs of early clinical stage SME biotechs on the East Coast and DACH.


    Connect with me:

    LinkedIn:https://www.linkedin.com/in/charles-spence-clinical/

    Website: https://www.discera-search.com/


    Opinions and comments expressed by the guest do not represent the company and are fully their own.


    Mehr anzeigen Weniger anzeigen
    41 Min.

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