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Herding Hemingway's Cats

Understanding How Our Genes Work

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Herding Hemingway's Cats

Von: Kat Arney
Gesprochen von: Kat Arney
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The language of genes has become common parlance. We know they make your eyes blue, your hair curly, or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism, or Alzheimer's. The cost of DNA sequencing has plummeted from billions of dollars to a few hundred, and gene-based advances in medicine hold huge promise.

So we've all heard of genes, but how do they actually work? According to legend, Ernest Hemingway was once given a six-toed cat by an old sea captain, and her distinctive descendants still roam the writer's Florida estate today. Scientists now know that the fault driving this profusion of digits lies in a tiny genetic control switch, miles away (in molecular terms) from the gene that "makes" toes. And it's the same mistake that gives rise to multi-toed humans too. There are 2.2 meters of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the "recipes" that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. And figuring out how it all works - how your genes make you, you - is a major challenge for researchers around the world. Drawing on stories ranging from six-toed cats and stickleback hips to wobbly worms and zombie genes, geneticist Kat Arney explores the how our genes work, creating a companion to the book of life itself.

©2016 Kat Arney (P)2015 Audible, Inc.
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Fun an facts in a great mix

This was such a joy to listen to! Kat Arney is not only a great scientist and science communicator but also a splendid voice-actress. The whole audiobook feels more like a report by several people Kat interviews (because she plays them in the audiobook, including accents) than just a book written by the author.
The facts are fascinating and it is a really deep dive in how our genes work, how our understanding has grown and the fact that the sum of things we do not know about our genes, the human genome and what does what in our DNA has grown more than the things we do know. Kat Arney points out several fascinating discoveries and their implications (sometimes with the help of excellent and fun voice acting) then takes a deep dive into those implications, the methods of discovery and possibilities for the future. The possibilities range from better tests to gene-editing to possible cures for genetic disorders (but do not hold your breath for those.
All is presented in an easy to understand and, I have to stress this, very fun way. There is a bulk of hard and dry science (even if it is squishy science) in here, but the way it is presented is neither hard, nor dry. This audiobook is a joy to listen to for the facts and the fun.

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